Background: Single pulmonary nodules are a common issue in the everyday clinical practice. Currently there are navigation systems with radial-ebus and electromagnetic navigation for obtaining biopsies. Moreover; rapid on site evaluation (ROSE) can be used for aquick assessment. These small lesions even when they do not have any clinical significant information with positron emission tomography it is important that are investigated. Radiofrequency and microwave ablation have been evaluated as local treatment techniques. These techniques can be used as therapy for a patient population that cannot be operated. Equipment and Methodology:Radial-Ebus and Rapid on Site Evaluation (ROSE) were used for diagnosis. PET-CT end CONVEX EBUS were used for statging. COVIDIEN radiofrequency probe with 25watts for 8minutes was used as an ablation system. Currently there is one verified operating system used for endoscopic radiofrequency ablation through the working channel of a bronchoscope. Results: Complete and succesful ablation was conducted, evaluation of the treatment was performed on site with the radial-ebus, computed tomography scan with i.v contrast and later with PET-CT. Conclusion: In our case a new system was used in order to perform radiofrequency ablation with long term follow up.