Background and Aim: Instrument for assessment of oral health related quality of life (OHRQoL) for edentulous subjects in Croatian cultural environment does not exist. The aim was to validate psychometric properties of the Croatian version of the Oral Health Impact Profile for edentulous population (OHIP-EDENT-CRO). Methods: The translation and cross-cultural adaptation were done according to accepted international standards. A total of 95 removable denture wearers were recruited. The reliability was evaluated by calculating the Cronbach's alpha coefficient. The test–retest was made in 30 participants. The concurrent validity was determined by calculating the Spearman's rank coefficient between the OHIP-EDENT summary scores and a question related to removable denture satisfaction. Construct validity was determined by exploratory factor analysis (EFA). Responsiveness was determined by comparison of the OHIP-EDENT summary scores before and after mini-dental implant (MDI) placement in the mandible for overdenture support (30 patients received 4 MDIs and 25 received 3 MDIs). Results: The Cronbach’s alpha coefficient was 9.22. The intraclass correlation coefficient was 0.98. The Spearman's correlation coefficient was -0.71 (p<0.001) which confirmed concurrent validity. Construct validity was tested by the EFA which extracted four factors, accounting for 66.59 % of the variance. Responsiveness was confirmed significant OHIP-EDENT summary score reduction and a high standardized effect size after MDI insertion. Conclusions: The results prove that the OHIP-EDENT-CRO has good psychometric properties for assessment of OHRQoL in edentulous population.

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