Aim of Purpose: To evaluate the oral health related quality of life (OHRQoL) after the implant therapy and prosthodontic rehabilitation with overdentures on 2 implants (ODI). Materials and methods: Thirteen patients (mean age = 64.50) fulfilled OHIP49-CRO questionnaire before receiving implants and 1-year after wearing overdenture. Another group of 130 healthy subjects (CHS) (age mean = 22.31) was randomly collected as a control group. Results: There were no significant differences for the OHIP scores between males and females and different age groups (<40, 40–59, >59), and no significant difference of the scores dependent on the presence of the natural teeth or FPD in the antagonistic jaw (P > 0.05). After 1 year, FPD follow-up scores were significantly lower in comparison to baseline scores, but still remained significantly higher than the CHS scores (P < 0.05). The highest effect size was in the group of patients that had the complete denture and received 2 implants, with result of 2.35 in the functional limitation group of OHIP questions. Conclusion: The implant-supported overdenture therapy significantly increased the OHRQoL, especially in the group of denture wearers, but didn’t reach the CHS group. Sex and age had no influence on the OHRQoL.
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